Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2018 Jul 17.

Published in final edited form as: Dev Biol. 2011 Dec 13;362(2):194–218. doi: 10.1016/j.ydbio.2011.12.009

Table 5.

Cell type counts after conditional Atoh1 deletion in Atoh1^fl/+ control and Atoh1^fl/fl experimental mice.

Genotype^a	Number of cells (mean±s.e.m.)

	Mucous cells (Alcian blue⁺)	Enteroendocrine cells (Insm1⁺)	Brush cells (Dclk1⁺Insm1⁻)
	Per crypt

Atoh1^fl/+;Rosa26^CreER/+	8.29±0.54 (138 crypts)	4.24±0.16 (126 crypts)	1.35±0.23 (126 crypts)
Atoh1^fl/fl;Rosa26^CreER/+	0.138±0.035^b (537 crypts)	0.205±0.080^b (237 crypts)	14.1±1.78^b (237 crypts)
	Per villus

Atoh1^fl/+;Rosa26^CreER/+	210±23.7 (31 villi)	31.2±3.58 (34 villi)	14.3±3.45 (34 villi)
Atoh1^fl/fl;Rosa26^CreER/+	0.140±0.047^b (98 villi)	1.62±0.38^b (50 villi)	73.8±10.2^b (50 villi)

^a

Data from 3 Tamoxifen treated mice of each genotype.

^b

Significantly different from corresponding Tamoxifen treated Atoh1^fl/+;Rosa26^CreER/+ control results.