Table 6.
Counts of the number of Gfi1b expressing cells per crypt after conditional Atoh1 deletion in Atoh1fl/+ control and Atoh1fl/fl experimental mice.
Genotypea | Number of cells per crypt (mean±s.e.m.) | |||
---|---|---|---|---|
|
|
|||
Gfi1b+ | Gfi1b+ Mki67+ | Gfi1b+ Dclk1+ | Gfi1b+ Dclk1+Mki67+ | |
Atoh1fl/+;Rosa26CreER/+ (242 crypts) | 1.6±0.19 | 0.14±0.03 | 1.45±0.21 | 0.025±0.002 |
Atoh1fl/fl;Rosa26CreER/+ (89 crypts) | 16.4±2.0b | 2.6±0.68b | 13.1±2.13b | 0.38±0.12b |
Data from 3 Tamoxifen treated mice of each genotype.
Significantly different from corresponding Tamoxifen treated Atoh1fl/+;Rosa26CreER/+ control results.