Table 1.
Baseline characteristics by race/ethnicity (N=5972)
| White (N=4827) |
African American (N=934) |
Hispanic (N=211) |
P-value | |
|---|---|---|---|---|
| Age, years | 70.5 ± 3.9 | 69.6 ± 3.8 | 68.7 ± 3.5 | <0.001 |
| Education | ||||
| Less than high school | 194 (4.0) | 106 (11.5) | 32 (15.4) | |
| High school | 955 (19.8) | 123 (13.3) | 35 (16.8) | <0.001 |
| Some college | 1930 (40.1) | 320 (34.6) | 71 (34.1) | |
| College graduate | 1735 (36.0) | 375 (40.6) | 70 (33.7) | |
| Pack years of smoking | ||||
| Never smoker | 2481 (53.5) | 454 (51.2) | 133 (64.6) | |
| <5 | 545 (11.7) | 122 (13.8) | 33 (16.0) | <0.001 |
| 5-<20 | 591 (12.7) | 136 (15.4) | 23 (11.2) | |
| ≥20 | 1024 (22.1) | 174 (19.6) | 17 (8.3) | |
| Alcohol consumption | ||||
| Non-drinker | 530 (11.1) | 150 (16.4) | 32 (15.5) | |
| Past drinker | 827 (17.2) | 312 (34.2) | 40 (19.3) | <0.001 |
| Current drinker | 3439 (71.7) | 451 (49.4) | 135 (65.2) | |
| Body mass index, kg/m2 | ||||
| Normal | 1611 (33.6) | 185 (20.0) | 61 (28.9) | |
| Overweight | 1788 (37.3) | 340 (36.8) | 93 (44.1) | <0.001 |
| Obese | 1391 (29.0) | 398 (43.1) | 57 (27.0) | |
| Total physical activity, MET-h/wk | 11.7 ± 12.8 | 10.1 ± 12.6 | 13.8 ± 14.9 | <0.001 |
| Hormone therapy use | ||||
| Never used hormones | 2333 (49.5) | 493 (53.4) | 88 (42.9) | |
| Past hormone user | 1597 (33.9) | 260 (28.1) | 45 (22.0) | <0.001 |
| Current hormone user | 780 (16.6) | 171 (18.5) | 72 (35.1) | |
| NSAID use | 877 (18.2) | 178 (19.1) | 37 (17.5) | 0.78 |
| History of chronic diseases | ||||
| CHD | 223 (4.7) | 65 (7.2) | 7 (3.4) | 0.005 |
| Cancer | 289 (6.1) | 91 (9.9) | 12 (5.7) | <0.001 |
| Diabetes | 259 (5.4) | 168 (18.0) | 14 (6.6) | <0.001 |
| COPD | 202 (4.5) | 42 (4.7) | 4 (2.0) | 0.21 |
| Natural logarithm serum CRP, mg/dl | 0.8 (1.0) | 1.1 (1.1) | 1.1 (1.0) | <0.001 |
| Unweighted genetic risk score from CRP SNPs among European populations | 2.2 ± 1.1 | 2.5 ± 1.1 | 2.1 ± 1.1 | <0.001 |
| Unweighted genetic risk score from published meta-analysis of CRP | 21.8 ± 2.6 | 21.6 ± 2.2 | 20.7 ± 2.8 | <0.001 |
Note. Data are presented as n (%) or mean (SD).