. Author manuscript; available in PMC: 2019 Aug 1.

Published in final edited form as: Osteoarthritis Cartilage. 2018 May 22;26(8):1038–1044. doi: 10.1016/j.joca.2018.05.002

Table 2.

Multivariable associations of serum ln hs-CRP with risk of total hip replacement for osteoarthritis

	ln hs-CRP, mg/l HR (95% CI)	P for trend
	White Women
Model 1^a	1.02 (0.87–1.19)	0.85
Model 2^b	0.96 (0.80–1.14)	0.62
Model 3^c	0.97 (0.81–1.17)	0.76
Model 4^d	0.96 (0.80–1.16)	0.67
	African American Women
Model 1^a	0.82 (0.57–1.18)	0.28
Model 2^b	0.71 (0.48–1.04)	0.08
Model 3^c	0.68 (0.45–1.02)	0.07
Model 4^d	0.69 (0.45–1.07)	0.09

CI, confidence interval; HR, hazard ratio.

Adjusted for age.

Adjusted for model 2 + body mass index.

Adjusted for model 3 + education, pack-years of smoking, alcohol consumption, and physical activity.

Adjusted for model 4 + chronic diseases (coronary heart disease, cancer, diabetes, and COPD), hormone therapy use, and non-steroidal anti-inflammatory drug use.