Table 3.
FISH analysis to evaluate for copy number alterations.
| Pre-treatment | Post-treatment | |||||||
|---|---|---|---|---|---|---|---|---|
| Patient ID | ALK FISH % cells positive | ALK FISH pattern | Abnormal ALK copy number/cell | ALK FISH | ALK FISH % cells positive | ALK FISH pattern | Abnormal ALK copy number/cell | ALK FISH |
| 7 | 28% | split | 0.3 sR, sG | Positive | 82% | split | 1.5 sR, sG | Positive |
| 8 | 48% | split | 0.5 sR,sG | Positive | 66% | split | 2.2 sR, sG | Positive |
| 20 | 76% | sR | 0.78 sR | Positive | 90% | sR | 1.92 sR | Positive |
| 22 | 76% | sR | 1.32 sR | Positive | 100% | sR | 3.08 sR | Positive |
| 24 | 72% | split | 1.66 sR, 1.68 sG | Positive | 98% | split | 3.68 sR, 3.92 sG | Positive |
| 31 | 46% | sR | 0.62 sR | Positive | 80% | sR | 1.84 sR | Positive |
Abbreviations – PT ID- patient ID, sR = single red, sG = single green, split = split red/green, mix = split red/green and single red
*
Rounded to the nearest tenth decimal