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. Author manuscript; available in PMC: 2019 Jul 1.

Published in final edited form as: J Labelled Comp Radiopharm. 2018 Mar 12;61(9):727–738. doi: 10.1002/jlcr.3605

Table 1.

Different antibody fragments and recommended PET radionuclide for companion diagnostic development.

Antibody Fragments	Recommended PET Nuclide	References
Affibody (~7 kDa), Nanobody (~12–15 kDa)	⁶⁸Ga ¹⁸F ⁶⁴Cu	^69–73
Diabody (~55 kDa)	¹⁸F ⁶⁴Cu ⁸⁹Zr	^74–76
Minibody (~80 kDa)	⁶⁴Cu ⁸⁹Zr	^77–78
Fab’₂ (~100–110 kDa)	⁶⁴Cu ⁸⁹Zr ¹²⁴I	⁷⁹