Table 3. Association between plasma ZFAS1 expression and clinical characteristics in HCC patients.
Characteristics | n | ZFAS1 relative expression(log) | ||
---|---|---|---|---|
Mean ± S.D. | t | P | ||
Plasma** | −7.60 | <0.001 | ||
HCC | 60 | −3.45 ± 0.51 | ||
Healthy controls | 79 | −4.01 ± 0.35 | ||
Gender | −0.735 | 0.465 | ||
Male | 54 | −3.47 ± 0.51 | ||
Female | 6 | −3.30 ± 0.55 | ||
Age | −0.942 | 0.35 | ||
<55 | 17 | −3.55 ± 0.56 | ||
≧55 | 43 | −3.41 ± 0.49 | ||
HBV DNA (IU/ml) | −0.704 | 0.485 | ||
<500 | 24 | −3.49 ± 0.50 | ||
≧500 | 23 | −3.40 ± 0.45 | ||
ALT (U/l) | −0.044 | 0.965 | ||
<46 | 29 | −3.46 ± 0.53 | ||
≧46 | 31 | −3.45 ± 0.50 | ||
AST (U/l) | 0.488 | 0.628 | ||
<46 | 25 | −3.42 ± 0.46 | ||
≧46 | 35 | −3.48 ± 0.55 | ||
GGT (U/l) | −0.53 | 0.598 | ||
<55 | 20 | −3.50 ± 0.48 | ||
≧55 | 40 | −3.43 ± 0.53 | ||
AFP (ng/l)* | −2.91 | 0.006 | ||
<200 | 20 | −3.64 ± 0.36 | ||
≧200 | 26 | −3.26 ± 0.49 | ||
CEA | 1.086 | 0.283 | ||
<5 | 42 | −3.41 ± 0.53 | ||
≧5 | 9 | −3.62 ± 0.51 |
Data are shown as mean ± S.D. Since we failed to collect all characteristics of the HCC patients, the total number may not be 60. Abrreviations: CEA, carcinoembyonic antigen
*P<0.05, **P<0.001.