Table 2. Frequencies of genotype and allele of CTSS and SIRT1 SNPs in the control and COPD groups.

SNP	Group	Genotype number			P	HWE P	Allele freq (%)		P	OR (95% CI)
rs12068264		TT	TC	CC			T	C
	Control	21	96	85	0.048	0.531	34.16%	65.84%	0.044	1.351 (1.008–1.811)
	COPD	35	80	67		0.222	41.21%	58.79%
rs11576175		AA	AG	GG			A	G
	Control	10	62	131	0.506	0.512	20.2%	79.8%	0.234	0.801 (0.555–1.155)
	COPD	6	49	126		0.600	16.85%	83.15%
rs16924934		GG	GA	AA			G	A
	Control	6	54	143	0.908	0.795	16.26%	83.74%	0.773	1.058 (0.724–1.546)
	COPD	5	52	125		1	17.03%	82.97%
rs2273773		CC	CT	TT			C	T
	Control	10	77	116	0.208	0.700	23.89%	76.11%	0.084	1.326 (0.962–1.828)
	COPD	15	77	90		0.860	29.4%	70.6%
rs3818291		AA	AG	GG			A	G
	Control	8	55	140	NA	0.340	17.49%	82.51%	0.868	0.969 (0.666–1.409)
	COPD	3	56	123		0.302	17.03%	82.97%

Abbreviation: Freq, frequency. NA, not available.