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Cellular targeting sequences and binding partners of EPAC1 (A) and EPAC2 (B). The mitochondrial targeting sequence (MTS), phosphatidic acid binding motif (PA-B), and nuclear pore localization sequence (NPLS) of EPAC1 are shown. In addition, protein binding partners of EPAC1 and EPAC2 and their interacting domains are depicted by arrows. See text for additional details and abbreviations.
