Table 2.

Results of the validation of the HFO detection and HFO area identification algorithm in peri-ictal epochs, by comparison with the clinically defined SOZ, for 12 representative subjects.

Patient	Method	TP	TN	FP	FN	Sensitivity (%)	CI (%)	Specificity (%)	CI (%)
1	Tukey	3	86	3	3	50	11.81–88.19	96.63	90.46–99.3
	k-means	4	71	17	2	66.67	22.28–95.67	80.68	70.88–88.32
2	Tukey	3	101	4	0	100	29.24–100	96.19	90.53–98.95
	k-means	3	92	13	0	100	29.24–100	87.62	79.76–93.24
3	Tukey	5	75	4	0	100	47.82–100	94.94	87.54–98.6
	k-means	5	78	1	0	100	47.82–100	98.73	93.15–99.97
4	Tukey	4	76	3	2	66.67	22.28–95.67	96.20	89.3–99.21
	k-means	4	77	2	2	66.67	22.28–95.67	97.47	91.15–99.69
5	Tukey	3	83	7	1	75	19.41–99.37	92.22	84.63–96.82
	k-means	3	89	1	1	75	19.41–99.37	98.89	93.96–99.97
6	Tukey	2	32	0	0	100	15.81–100	100	89.11–100
	k-means	2	28	4	0	100	15.81–100	87.50	71.01–96.49
7	Tukey	2	17	1	1	66.67	9.43–99.16	94.44	72.71–99.86
	k-means	3	15	2	0	100	29.24–100	88.24	63.56–98.54
8	Tukey	1	20	0	1	50	15.81–100	84.21	60.42–96.62
	k-means	1	17	3	1	50	1.26–98.74	85	62.11–96.79
9	Tukey	5	23	1	1	83.33	35.88–99.58	95.83	78.88–99.89
	k-means	6	20	3	0	100	54.07–100	86.96	66.41–97.22
10	Tukey	2	23	1	2	50	6.76–93.24	95.83	78.88–99.89
	k-means	2	18	6	2	50	6.76–93.24	75	53.29–90.23
11	Tukey	3	16	2	4	42.86	9.9–81.59	88.89	65.29–98.62
	k-means	3	15	3	4	42.86	9.9–81.59	83.33	58.58–96.42
12	Tukey	2	22	6	1	66.67	9.43–99.16	82.14	63.11–93.94
	k-means	3	17	10	0	100	29.24–100	62.96	42.37–80.6