Table 2.
Endothelial-related genes PCR array.
| No. | Down-regulated genes | Gene name | Fold-regulation |
|---|---|---|---|
| 1 | TFPI | Tissue factor pathway inhibitor | –5.8685∗∗ |
| 2 | SPHK | Sphingosine kinase 1 | –5.0771∗∗ |
| 3 | FAS1 | TNF receptor superfamily, member 6 | –4.4878∗ |
| 4 | PLGF | Placental growth factor | –3.9132∗∗ |
| 5 | TIE-2 | TEK tyrosine kinase, endothelial | –3.4943∗ |
| 6 | CGL3 | Caveolin 1, caveolae protein, 22kDa | –3.2595∗ |
| 7 | CASP8AP1 | CASP8 and FADD-like apoptosis regulator | –2.8613∗∗ |
| 8 | IL-6 | Interleukin 6 (interferon, beta 2) | –2.8284∗∗ |
| 9 | CD31 | Platelet/endothelial cell adhesion molecule | –2.484∗ |
| 10 | CPP32 | Caspase 3, cysteine peptidase | –2.0378∗ |
| 11 | ITGA5 | Integrin, alpha 5 | –1.5562∗ |
| 12 | MMP-2 | Matrix metallopeptidase 2 | –1.4746∗ |
| 13 | KNO | Collagen, type XVIII, alpha 1 | –1.4119∗ |
| 14 | BCL2L1 | BCL2-like 1 | –1.3007∗ |
Genes down-regulated in VPA-treated vs. control ECs. ∗p < 0.05, ∗∗p < 0.01 and ∗∗∗p < 0.001 vs. control group.