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. 2018 Jul 11;9:907. doi: 10.3389/fphys.2018.00907

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Copyright © 2018 Rouhimoghadam, Safarian, Carroll, Sheibani and Bidkhori.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Study of the cell distribution in different cell cycle stages. (Left) MCF-7 cells incubated with tamoxifen, and (Right) control cells. The bell-shaped curves from left to right correspond to the G1, S, G2/M phases of the cell cycle in the control and cells incubated with tamoxifen. Incubation of cells with tamoxifen did not significantly shift the distribution of the cells in different phases of the cell cycle compared with control. As in the treated group, there were minor increases, about 10 and 6%, in the S and G2 phases of the cell cycle, respectively.