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. 2018 Apr 24;11(3):743–754. doi: 10.1016/j.tranon.2018.03.013

Figure 3.

Figure 3

Different gene expression profiles of HBsAg-transgenic mice in the presence or absence of PML during HCC development. Comparison of transcriptional profiling in the livers of wild-type, HBsAgtg/0, PML−/− and PML−/-HBsAgtg/0 mice with different ages, sex and pathology. (A) Internal control. (B) Lipogenic genes. (C) Inflammation and apoptosis genes. Error bars indicate mean ± SEM from 3 independent experiments. Note that the up-regulation of Scd1 mRNA levels is in concordance with HCC development in PML−/-HBsAgtg/0 mice.