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. 2018 Apr 24;11(3):743–754. doi: 10.1016/j.tranon.2018.03.013

Figure S1.

Figure S1

Divergent alterations in liver proteomics between 6-month-old mice with cytoplasmic ground change and 14-month-old mice with dysplasia in HBsAgtg/0male mice. The enriched genes, whose expression was 2-fold up-regulated or down-regulated in more than 50% of the genetically engineered mice (n = 10 for each genotype) compared to the average expression of the same genes in sex- and age-matched wild-type mice (n = 5 for each group), were categorized by gene ontology (GO) analysis. Note that the divergent expression of proteins is involved in energy metabolism, cell cycle regulation, transcription, antigen presentation and chromatin remodeling.