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. 2018 Apr 12;19:174–181. doi: 10.1016/j.nicl.2018.04.011

Table 2.

Comparison of NODDI and DTI parameters between groups for tumour differentiation and IDH-1 status.

Variables Tumour differentiation
IDH-1 status
LGG (n = 18) HGG (n = 24) P Negative (n = 18) Positive (n = 23) P
TP
 icvf 0.246 ± 0.130 0.401 ± 0.119 <0.001 0.357 ± 0.128 0.322 ± 0.159 0.441
 ODI 0.299 ± 0.058 0.360 ± 0.078 0.009 0.340 ± 0.058 0.327 ± 0.089 0.591
 FA 0.138 ± 0.041 0.174 ± 0.049 0.015 0.171 ± 0.050 0.152 ± 0.046 0.208
 MD (×10−3 mm2/s) 1.609 ± 0.321 1.299 ± 0.272 0.002 1.379 ± 0.345 1.461 ± 0.321 0.436
PT
 icvf 0.448 ± 0.130 0.315 ± 0.155 0.006 0.321 ± 0.142 0.410 ± 0.165 0.075
 ODI 0.278 ± 0.089 0.245 ± 0.065 0.180 0.243 ± 0.074 0.262 ± 0.067 0.402
 FA 0.284 ± 0.088 0.212 ± 0.088 0.012 0.228 ± 0.074 0.259 ± 0.108 0.309
 MD (×10−3 mm2/s) 1.085 ± 0.229 1.458 ± 0.373 0.001 1.373 ± 0.327 1.251 ± 0.398 0.301
TP/NAWM
 icvf 0.437 ± 0.242 0.770 ± 0.241 <0.001 0.701 ± 0.279 0.576 ± 0.300 0.179
 ODI 1.295 ± 0.498 1.679 ± 0.571 0.028 1.658 ± 0.578 1.404 ± 0.561 0.164

TP: tumour parenchyma; PT: peritumoural area; NAWM: normal-appearing white matter; icvf: intracellular volume fraction; ODI: orientation dispersion index; FA: fractional anisotropy; MD: mean diffusion.