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. 2018 May 25;22(8):3955–3964. doi: 10.1111/jcmm.13675

Figure 7.

Figure 7

LncRNA ABHD11‐AS1 promotes the development of endometrial cancer by targeting cyclin D1. Silencing of cyclin D1 in ABHD11‐AS1‐overexpressing Ishikawa cells significantly inhibited proliferation (A), induced G1 phase arrest (B) and apoptosis (C), inhibited migration (D) and invasion (E). Western blotting showed that silencing of cyclin D1 reversed the ability of ABHD11‐AS1 to up‐regulate cyclin D1, CDK1, CDK2, CDK4, Bcl‐xl and VEGFA and down‐regulate p16 expression (F)