Table 1. Apparent rate and equilibrium constants for the small-molecule model study. Data are the average of three experiments performed at 25 °C.

Configuration	K eq a	k 1 a (s–1)	k –1 a (s–1)	k –1 b (s–1)
E	0.090 ± 0.016	2.56 ± 0.28 × 10–5	2.76 ± 0.32 × 10–4	2.83 ± 0.06 × 10–4
Z	0.39 ± 0.024	5.39 ± 0.45 × 10–5	1.39 ± 0.20 × 10–4	1.45 ± 0.10 × 10–4
Z/E	4.3	2.11	0.504	0.512

^aApparent equilibrium constants and rate constants obtained from the reversible esterification experiment.

^bApparent rate constants obtained from the irreversible hydrolysis experiments.