Table 4. Effect of α-substituent on coumarins in enantioselective allylic alkylation ^a .

Entry	X	t [h]	3	Yield b [%]	er c
1	CN (1a)	36	3aa	86	98 : 2
2	CONH2 (1i)	36	3ia	81	98 : 2
3	CO2Et (1j)	48	3ja	80	97.5 : 2.5
4	CO2Bn (1k)	48	3ka	85	98 : 2
5	CO2H (1l)	42	3la	<5 d	—
6	H (1m)	48	3ma	<5	—

^aReaction conditions: 3 mol% [Ir(COD)Cl]₂, 6 mol% L1, 0.24 mmol of 1, 0.2 mmol of 2a and 0.2 mmol of DABCO in 0.6 mL CH₂Cl₂. The catalyst was prepared via n-PrNH₂ activation.

^bYields correspond to the isolated product after chromatographic purification.

^cer was determined by HPLC analysis on a chiral stationary phase.

^d 1m was isolated in 52% yield.