Table 1.
Aerosol | IV | |
---|---|---|
Lung AUC (h·µg/g) | 66.5 | 1.07 |
Blood AUC (h·µg/g) | 3.55 | 10.7 |
AUC ratio (Lung/Blood) | 18.8 | 0.01 |
Lung AUC ratio (Aero/IV) | 62.0 | |
Blood AUC ratio (IV/Aero) | 3.0 | |
Lung Cmax (µg/g) | 10.6 | 0.38 |
Blood Cmax (µg/g) | 0.28 | 5.09 |
t1/2.lung (h) | 2.3 | 2.0 |
t1/2.blood (h) | N/A | 0.8 |