Table 4.

Generalized linear models of the effects of the IL6 -174G/C polymorphism on the body composition of severely obese individuals after a 12-week nutritional intervention

Variables	Weight change			Fat mass change
	Adj. β*	95% CI	P	Adj. β*	95% CI	P
Intercept	3.969	− 4.212, 11.348	0.369	−0.754	−9.145, 7.363	0.860
Age	0.026	−0.068, 0.121	0.585	−0.027	−0.112, 0.586	0.541
Gender
Females	0	Reference		Reference
Males	−2.411	−4.752, −0.070	0.044	1.281	−1.725, 4.286	0.404
Baseline BMI	−0.053	−0.188, 0.081	0.437	0.071	−0.110, 0.253	0.442
Sedentary time change	0.008	−0.005, 0.021	0.235	0.003	−0.008, 0.142	0.588
Nutritional intervention
OO	0	Reference		Reference
DieTBra	−4.980	−7.103, −2.858	< 0.001	−1.495	−3.390, 0.400	0.122
DieTBra+OO	−4.406	−6.478, −2.335	< 0.001	−1.975	−3.798, −0.153	0.034
-174G > C polymorphism
GG	0	Reference		Reference
C carriers	−0.219	−1.956, 1.519	0.805	−0.015	−1.513, 1.484	0.985

Dependent variables: 12^th week measurement – baseline measurement. OO olive oil group, DieTBra traditional Brazilian diet group, DieTBra + OO traditional Brazilian diet plus olive oil group, BMI Body Mass Index

*General linear models were adjusted for age, gender, baseline BMI and change in sedentary time. When interactions were tested (SNP x nutritional intervention, gender x nutritional intervention), the P value was not significant (P > 0.05). Data for the outcomes fat-free mass, body fat percentage and lean mass were not significant