Figure 1.

The effect of calcium electroporation (CaEP) on normal and cancer cell spheroids. In a spheroid study, colon cancer cell spheroids and normal dermal fibroblast spheroids were treated with CaEP. No decrease in spheroid size or viability was seen in normal cell spheroids, while a significant decrease in size and viability was observed in the colon cancer spheroids. The spheroids were treated 5 days after seeding the cells and due to differences in doubling time the size of the spheroids differs at treatment time. Adapted from Frandsen, Gibot et al, 2015.⁴⁶