Table 3.
Independent clinical characteristics associated with NGS tuft volume in both kidney donors and patients with renal tumor up to age 75 years
| Clinical Characteristic | Multivariable Adjusteda | |
|---|---|---|
| Kidney Donors and Patients with Renal Tumor (n=2447) | ||
| % Difference | P Value | |
| Age per 10 yr (up to age 75 yr) | 0.1 | 0.93 |
| Men | 9.5 | <0.001 |
| Height per SD | 2.1 | 0.04 |
| BMI per SD | 8.4 | <0.001 |
| Hypertension | 3.8 | 0.09 |
| Diabetes | 13.6 | 0.008 |
| eGFR per SD | 1.9 | 0.06 |
| Family history of ESRD | 7.3 | <0.001 |
| 24-h urine protein per doubling, mgb | 2.5 | <0.001 |
| Patients with renal tumor versus kidney donors | 1.8 | 0.49 |
The mean SD across both populations was used (9.6 cm for height, 5.3 kg/m2 for body mass index [BMI], 19.5 ml/min for eGFR).
a
Adjusted for each other characteristic.
b
If 24-hour urine protein was excluded, findings were similar except hypertension was also associated with larger NSG tuft volume (6.2% larger; P=0.002).