Table 2.
Residual function, dialysis prescription parameters, and kinetic measures
| Parameter | Twice Weekly | Thrice Weekly | P Value |
|---|---|---|---|
| Kru, ml/min | 2.8±1.5 | — | — |
| Urine output, ml/d | 832±422 | — | — |
| Weekly ultrafiltration, L/wk | 4.2±2.6 | 7.2±2.5 | 0.02 |
| Dialysis time, min/wk | 369±22 | 605±81 | <0.001 |
| spKt/Vurea | 1.51±0.21 | 1.58±0.19 | 0.39 |
| 2015 KDOQI stdKt/Vurea | 2.53±0.53a | 2.41±0.14 | 0.49 |
| Original stdKt/Vurea | 2.25±0.39 | 2.41±0.14 | 0.11 |
| Blood flow, ml/min | 367±66 | 400 | 0.44 |
| Dialysate flow, ml/min | 589±93 | 713±98 | 0.01 |
Results are mean±SD. 2015 KDOQI stdKt/Vurea and original stdKt/Vurea values were obtained as described in the Methods and Supplemental Material. Urine output was estimated from a 3 day collection period. The weekly ultrafiltration was the sum of the ultrafiltration for treatments during the week of sample collection. Dialyzers used were Revaclear/Revaclear 300/Revaclear Max/F160/F180 with frequency 4/1/0/3/1 and 6/0/3/0/0 in the twice weekly and thrice weekly groups, respectively. Kru, residual urea clearance; —, no data.
P<0.05, 2015 KDOQI versus original stdKt/Vurea.