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Properdin deficiency prevented macrovessel thrombosis in FHR/R mice. Hematoxylin and eosin staining of (A) liver, (B) kidney, (C) lung, and (D) spleen showed that macrovessel thrombi (yellow arrows) were present in FHR/R mice but not in FHW/W or FHR/R P−/− mice. Scale bars, 100 μm.
