FIG 7 .

A model for the role of HtrABb through proteolysis of P66, Hbb, and three enzymes of the glycolytic pathway in a potential decrease in metabolic activity of B. burgdorferi. Proteolytic degradation of P66 could limit the amount of essential nutrients required for motility or for production of energy. Proteolytic degradation of glycolytic enzymes could result in a decrease of energy-producing molecules. The combined net effect of proteolysis of P66 and enzymes would be to prepare B. burgdorferi for the stage that requires lower metabolic activity.