Table 1.
Characteristics of participants (n=26).
| Characteristics | Healthy controls n=13 |
COPD participants n=13 |
P-value |
|---|---|---|---|
| Sex (M/F) | 9 /4 | 9 / 4 | 1.00§ |
| Age (y) | 63.4 ± 6.9 | 65.2 ± 7.6 | 0.52¥ |
| BMI (kg/m2) | 24.3 ± 2.6 | 22.6 ± 3.4 | 0.17¥ |
| % Fat | 28.9 ± 7.9 | 27.0 ± 7.8 | 0.53¥ |
| Lean body mass (Kg) | 41.7 ± 8.3 | 39.2 ± 8.4 | 0.44¥ |
| Fat body mass (Kg) | 16.9 ± 4.8 | 14.5 ± 4.3 | 0.19¥ |
| Bone mass (g/cm2) | 1.1 ± 0.1 | 1.0 ± 0.1 | 0.23£ |
| FEV1 (l) | 2.6 ± 0.3 | 1.5 ± 0.6 | <0.001∗¥ |
| FVC (l) | 3.4 ± 0.5 | 2.1 ± 0.8 | 0.01∗¥ |
| FEV1 postBD (% pred) | 99.6 ± 12.5 | 58.1 ± 19.2 | <0.001∗¥ |
| FEV1/FVC (%) | 76.9 ± 3.5 | 57.6 ± 9.1 | <0.001∗¥ |
| 6MWT (m) | 574.3 ± 18.8 | 445.7 ± 25.6 | <0.001∗¥ |
| Handgrip strength# (KgF) | 34.3 ± 2.4 | 34.8 ± 2.9 | 0.90¥ |
| Pack-years (n) | 12.5 ± 4.2 | 35.9 ± 6.3 | 0.006∗£ |
Means ±SD. §Chi square test; ¥unpaired t-test; £Mann–Whitney test; ∗statistical significance. BMI: body mass index; FEV1: forced expiratory volume in the first second; FVC: forced vital capacity; 6MWT: 6-minute walking test.# df=20.