Table 1.
Histopathological NAS score evaluation. Degree of steatosis and NASH (grade 0 ≤ 5%; 1 = 5–33%; grade 2 = 34%–66%; grade 3 ≥ 66%), lobular inflammation (0: no foci, 1 < 2 foci per 200x field, 2: 2 to 4 foci per 200x field, and 3: foci per 200x field), hepatocyte ballooning (0: none; 1: rare or few; 2: many), and fibrosis (0: no fibrosis, 1: perisinusoidal or periportal fibrosis, 2: perisinusoidal and portal/perioral fibrosis, 3: bridging fibrosis, and 4: cirrhosis).
NAS pathological score factors | Control | HF | HF + CoPP | HF + CoPP + SnMP |
---|---|---|---|---|
Steatosis | 0 (0.67%) | 2 (42.24%) | 1 (10.28%) | 2 (33.05%) |
Inflammation | 0 (no foci) | 2 (2-4 foci/field) | 1 (<2 foci/field) | 2 (2-4 foci/field) |
Ballooning | 1 (rare) | 2 (many) | 1 (rare) | 2 (many) |
Fibrosis | 0 (no fibrosis) | 3 (bridging fibrosis) | 0 (no fibrosis) | 2 (perisinusoidal and portal fibrosis) |
NAS value | 1 | 9 NASH | 3 | 8 NASH |