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. 2018 Jun 1;7(7):3342–3350. doi: 10.1002/cam4.1570

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© 2018 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Knockdown of LINC00857 expression in T24 and UM‐UC‐3 bladder cancer cell lines. A, The LINC00857 expression levels 48 hours after siRNA‐mediated knockdown. The effect of LINC00857 knockdown on (B) cell viability, (C) induction of apoptosis analyzed by caspase 3/7 activity, and (D) number of colonies formed in a colony‐forming assay (evaluated 2 weeks after transfection). All data are compared to negative control (NC1) siRNA‐transfected cells. All bars represent the mean ± SD (t test, *P < .05; **P < .01; ***P < .001)