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. 2018 Jun 1;7(7):3342–3350. doi: 10.1002/cam4.1570

Figure 5.

Figure 5

LINC00857 target gene expression and cisplatin sensitization in T24 and UM‐UC‐3 bladder cancer cells. Expression of LINC00857 target genes DIAPH3,LMAN1,PPP2R5E, and UHMK1 in (A) T24 and (B) UM‐UC‐3 bladder cancer cell lines upon LINC00857 knockdown. All data are compared to NC1‐siRNA‐transfected cells. C, Cisplatin sensitivity of UM‐UC‐3 cells 48 h after siRNA‐mediated knockdown of LMAN1 and PPP2R5E. Cell viability was normalized to non‐cisplatin‐treated cells. D, The efficiency of gene knockdown in siRNA‐transfected UM‐UC‐3 cells. Gene expression levels were normalized against GAPDH housekeeping gene expression levels and then compared to negative control (NC1) siRNA‐transfected cells. Bars and graphs represent the mean ± SD (t test, *P < .05; **P < .01; ***P < .001)