Figure 1.

LACTB is frequently dysregulated expression in cancers. A, LACTB mRNA expression level in TCGA data analysis. LACTB mRNA was upregulated in tumor tissues of esophagus cancer (ESCA), stomach cancer (STAD), and cervical cancer (CESC), whereas low downregulated in lung cancer (LUAD), liver cancer (LIHC), and colon cancer (COAD), there was no significant difference in breast cancer (BRCA), rectal cancer (READ), thyroid cancer (THCA), and renal cancer (KIRC). B, LACTB protein expression in pan‐cancer tissues and paired non‐tumor samples. LACTB protein was upregulated in tumor tissues of lung cancer, esophagus cancer, thyroid cancer, stomach cancer, and colon cancer, whereas low downregulated in liver cancer and breast cancer, there was no significant difference in renal cancer, rectal cancer, and cervical cancer. C, Representative LACTB histologic scoring in pan‐cancer tissues and paired non‐tumor samples