Table 4.
Cancer site | Race | Diabetes status | N | HR | 95% CI | P‐values |
---|---|---|---|---|---|---|
Bladder | White | Without diabetes | 12 104 | Ref | ~ | <.0001 |
With diabetes | 2844 | 1.21 | 1.16‐1.28 | |||
Black | Without diabetes | 764 | 1.24 | 1.14‐1.36 | ||
With diabetes | 414 | 1.32 | 1.18‐1.48 | |||
Cervix | White | Without diabetes | 2154 | Ref | ~ | .0047 |
With diabetes | 553 | 1.19 | 1.07‐1.33 | |||
Black | Without diabetes | 476 | 1.08 | 0.96‐1.21 | ||
With diabetes | 190 | 1.18 | 1.00‐1.39 | |||
Colon/Rectum | White | Without diabetes | 48 648 | Ref | ~ | <.0001 |
With diabetes | 13 112 | 1.19 | 1.16‐1.22 | |||
Black | Without diabetes | 4693 | 1.14 | 1.10‐1.18 | ||
With diabetes | 2493 | 1.21 | 1.16‐1.27 | |||
Corpus/Uterus | White | Without diabetes | 17 241 | Ref | ~ | <.0001 |
With diabetes | 5502 | 1.26 | 1.22‐1.31 | |||
Black | Without diabetes | 1518 | 1.54 | 1.44‐1.63 | ||
With diabetes | 986 | 1.66 | 1.54‐1.79 | |||
Female Breast ER ‐ | White | Without diabetes | 11 905 | Ref | ~ | <.0001 |
With diabetes | 2737 | 1.24 | 1.18‐1.30 | |||
Black | Without diabetes | 1402 | 1.27 | 1.19‐1.37 | ||
With diabetes | 773 | 1.29 | 1.19‐1.41 | |||
Female Breast ER + | White | Without diabetes | 67 613 | Ref | ~ | <.0001 |
With diabetes | 15 505 | 1.24 | 1.21‐1.27 | |||
Black | Without diabetes | 3912 | 1.15 | 1.11‐1.21 | ||
With diabetes | 2248 | 1.39 | 1.32‐1.47 | |||
Hodgkin Lymphoma | White | Without diabetes | 731 | Ref | ~ | .0107 |
With diabetes | 229 | 1.27 | 1.07‐1.51 | |||
Black | Without diabetes | 40 | 0.94 | 0.63‐1.41 | ||
With diabetes | 25 | 1.62 | 1.02‐2.56 | |||
Liver | White | Without diabetes | 1989 | Ref | ~ | .0099 |
With diabetes | 1293 | 1.09 | 1.02‐1.18 | |||
Black | Without diabetes | 229 | 0.92 | 0.80‐1.06 | ||
With diabetes | 161 | 1.18 | 1.00‐1.39 | |||
Myeloma | White | Without diabetes | 5168 | Ref | ~ | <.0001 |
With diabetes | 1249 | 1.20 | 1.12‐1.28 | |||
Black | Without diabetes | 989 | 1.01 | 0.94‐1.09 | ||
With diabetes | 461 | 1.07 | 0.97‐1.19 | |||
Non‐Hodgkin Lymphoma | White | Without diabetes | 18 022 | Ref | ~ | <.0001 |
With diabetes | 4415 | 1.29 | 1.24‐1.34 | |||
Black | Without diabetes | 806 | 1.10 | 1.01‐1.20 | ||
With diabetes | 422 | 1.44 | 1.29‐1.61 | |||
Ovary | White | Without diabetes | 11 738 | Ref | ~ | <.0001 |
With diabetes | 2547 | 1.23 | 1.17‐1.29 | |||
Black | Without diabetes | 733 | 1.22 | 1.13‐1.32 | ||
With diabetes | 401 | 1.40 | 1.26‐1.56 | |||
Pancreas | White | Without diabetes | 11 699 | Ref | ~ | <.0001 |
With diabetes | 5368 | 1.11 | 1.07‐1.15 | |||
Black | Without diabetes | 1202 | 1.10 | 1.04‐1.17 | ||
With diabetes | 1148 | 1.24 | 1.16‐1.31 | |||
Stomach | White | Without diabetes | 4806 | Ref | ~ | .4339 |
With diabetes | 1681 | 0.97 | 0.91‐1.03 | |||
Black | Without diabetes | 878 | 1.02 | 0.94‐1.10 | ||
With diabetes | 519 | 1.05 | 0.95‐1.16 |
CI, confidence interval; ER, estrogen receptor; HR, hazard ratio; SEER, Surveillance, Epidemiology, and End Results.
All models adjusted for age, stage, comorbidities, and treatment.