Figure 1.

Identification of NDR1 as a potential metastasis suppressor gene. Gene expression analysis of 6 major signaling pathways involved in metastasis of PC3 cells (HIPPO, MAPK, NOTCH, WNT, PI3K‐Akt, and NF‐κB) using cDNA microarrays. NDR1, a member of HIPPO pathway, was chosen for further research (the black arrow). The figure shows different expression in 19 Hippo pathway associated genes between PC3 and CTCs cell line. NDR1 fold change in CTCs vs PC3 was −5.13, with a P value = .00018