Table 1.
Demographic and clinical features of patients with newly diagnosed NB (N = 79)
| Characteristics | Total cases, N (%) |
|---|---|
| Age (mo) | |
| <18 | 19 (24.1) |
| ≥18 and <60 | 48 (60.8) |
| ≥60 | 12 (15.2) |
| Sex | |
| Female | 32 (40.5) |
| Male | 47 (59.5) |
| Primary site | |
| Abdomen | 64 (81.0) |
| Thorax and other | 15 (19.0) |
| Tumor size | |
| >10 cm | 42 (53.2) |
| ≤10 cm | 37 (46.8) |
| Tumor stage | |
| II/III | 15 (19.0) |
| IV | 64 (81.0) |
| MYCN gene | |
| Amplification | 15 (19.0) |
| Nonamplification | 64 (81.0) |
| NSE (ng/mL) | |
| <370 | 46 (58.2) |
| ≥370 | 33 (41.8) |
| LDH (IU/L) | |
| ≤500 | 32 (40.5) |
| >500 and <1500 | 30 (38.0) |
| ≥1500 | 17 (21.5) |
| Metastatic site | |
| Bone | 51 (64.6) |
| Bone marrow | 52 (65.8) |
| Distant lymph node | 49 (62.0) |
| Liver | 14 (17.7) |
| Central nervous system | 12 (15.2) |
| Number of organs with metastasis | |
| <3 | 40 (50.6) |
| =3 | 25 (31.6) |
| >3 | 14 (17.7) |
LDH, lactate dehydrogenase; NB, neuroblastoma; NSE, neuron‐specific enolase.