Table 3.
Serum NSE and LDH levels and total plasma cfDNA in the stable disease NB group
| Characteristics | N | NSE median (min‐max ng/mL) | LDH median (min‐max IU/L) | cfDNA median (min‐max ng/mL) | cfDNA integrity median (min‐max) |
|---|---|---|---|---|---|
| Age (mo) | |||||
| <18 | 1 | 28.7 (28.7‐28.7) | 261 (261‐261) | 8.85 (8.85‐8.85) | 0.24 (0.24‐0.24) |
| ≥18 and <60 | 38 | 25.20 (15.0‐84.3) | 275 (68‐454) | 7.03 (3.02‐28.17) | 0.22 (0.10‐0.41) |
| ≥60 | 40 | 22.85 (16.2‐52.4) | 256 (167‐379) | 6.445 (2.44‐24.53) | 0.21 (0.12‐0.35) |
| Sex | |||||
| Female | 37 | 23.5 (15.0‐52.7) | 271 (195‐454) | 6.74 (2.96‐25.07) | 0.21 (0.10‐0.41) |
| Male | 42 | 23.95 (16.5‐84.3) | 260.5 (68‐379) | 6.855 (2.44‐28.17) | 0.23 (0.12‐0.39) |
| Primary site | |||||
| Abdomen | 55 | 23.7 (16.2‐84.3) | 268 (195‐454) | 6.80 (2.44‐28.17) | 0.21 (0.10‐0.35) |
| Thorax and other | 24 | 23.7 (15.0‐52.4) | 265 (68‐365) | 7.12 (2.96‐24.53) | 0.24 (0.12‐0.41) |
| Maintenance therapy | |||||
| None | 48 | 23.6 (15.0‐52.4) | 265.5 (68‐454) | 6.635 (2.44‐24.53) | 0.23 (0.10‐0.41) |
| Retinoic acid | 31 | 23.9 (16.5‐84.3) | 268 (195‐369) | 6.91 (3.34‐28.17) | 0.21 (0.13‐0.35) |