Table 1.

Components of HCC staging and prognostic systems

Systems	PS	Tumor‐related factors				Liver function			AFP	Prior Tx	LiverDxb
		Size	Nodes	PVT	Extenta	CP	Alb	Bili
TNM7	✖	✔	✔	✔	✖	✖	✖	✖	✖	✖	✖
BCLC	✔	✔	✖	✔	✖	✔	✖	✔	✖	✖	✖
CLIP	✖	✔	✖	✔	✔	✔	✖	✔	✔	✖	✖
Okuda	✖	✔	✖	✖	✔	✖	✔	✔	✖	✖	✖
ALBI	✖	✖	✖	✖	✖	✖	✔	✔	✖	✖	✖

AFP, alpha‐fetoprotein; Alb, albumin; ALBI, albumin–bilirubin grade; BCLC, Barcelona Clinic Liver Cancer; Bili, bilirubin; CLIP, Cancer of Liver Italian Program; CP, Child–Pugh classification; HCC, hepatocellular carcinoma; PS, performance status; PVT, portal vein thrombosis; TNM7, TNM staging seventh edition; Tx, treatment.

^aExtent of primary tumor compared to liver area (greater or less than 50%).

^bEtiology of liver disease.