Figure 3.

Effect of menhaden oil concentration with or without salsalate on vascular relaxation by calcitonin gene-related peptide in epineurial arterioles of the sciatic nerve in Sprague Dawley type 2 diabetic rats. Pressurized arterioles (40 mmHg and ranging from 60 to 100 μm luminal diameters) were constricted with phenylephrine (30–50%), and incremental doses of calcitonin gene-related peptide were added to the bathing solution while recording steady-state vessel diameter. The number of rats in each group was the same as shown in Table 1. Data are presented as the mean of % relaxation ± SEM. ^∗P < 0.05 compared to control rats; ⁺P < 0.05 compared to diabetic rats.