Table 1.
Condition | Start weight (g) | End weight (g) | Chow consumed (g/kg body weight/day) | Blood glucose (mg/dl) | Serum triglycerides (mg/ml) | Serum-free fatty acids (mmol/L) | Serum cholesterol (mg/ml) |
---|---|---|---|---|---|---|---|
Control (12) | 336 ± 3 | 494 ± 13 | 50.5 ± 3.0 | 147 ± 6 | 32.7 ± 5.8 | 0.13 ± 0.02 | 0.91 ± 0.02 |
Diabetic (12) | 335 ± 2 | 439 ± 9 | 58.0 ± 3.8 | 478 ± 35a | 192.3 ± 18.4a | 0.37 ± 0.05a | 1.95 ± 0.06a |
Diabetic + salsalate (12) | 333 ± 3 | 451 ± 12 | 48.0 ± 3.5 | 443 ± 40a | 125.1 ± 25.9 | 0.36 ± 0.03a | 1.73 ± 0.20a |
Diabetic + menhaden oil 10% (12) | 322 ± 3 | 420 ± 9 | 48.9 ± 3.3 | 469 ± 20a | 246.4 ± 30.2a | 0.42 ± 0.06a | 1.53 ± 0.17a |
Diabetic + menhaden oil 10% + salsalate (12) | 326 ± 2 | 439 ± 21 | 50.9 ± 3.2 | 396 ± 43a | 102.4 ± 25.0 | 0.32 ± 0.05a | 1.55 ± 0.17a |
Diabetic + menhaden oil 25% (12) | 309 ± 4 | 426 ± 21 | 64.5 ± 4.6 | 500 ± 16a | 316.9 ± 37.5a | 0.41 ± 0.04a | 2.81 ± 0.22a |
Diabetic + menhaden oil 25% + salsalate (12) | 305 ± 4 | 415 ± 14 | 58.2 ± 3.8 | 478 ± 39a | 119.4 ± 26.2 | 0.35 ± 0.03a | 1.78 ± 0.15a |
Diabetic + menhaden oil 45% (12) | 335 ± 3 | 459 ± 18 | 57.9 ± 4.3 | 426 ± 42a | 82.6 ± 13.0a,b | 0.40 ± 0.06a | 1.96 ± 0.14a |
Diabetic + menhaden oil 45% + salsalate (12) | 315 ± 5 | 438 ± 14 | 67.2 ± 5.7 | 431 ± 35a | 68.9 ± 18.6b | 0.17 ± 0.04 | 1.33 ± 0.18 |
Data are presented as the mean ± SEM. aP < 0.05 compared to control rats. bP < 0.05 compared to diabetic rats. Parentheses indicate the number of experimental animals.