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. 2018 Jul 2;2018:2967127. doi: 10.1155/2018/2967127

Table 1.

Effect of menhaden oil with or without salsalate on weight, chow consumed, serum triglycerides, free fatty acids, and cholesterol in type 2 diabetic Sprague Dawley rats.

Condition Start weight (g) End weight (g) Chow consumed (g/kg body weight/day) Blood glucose (mg/dl) Serum triglycerides (mg/ml) Serum-free fatty acids (mmol/L) Serum cholesterol (mg/ml)
Control (12) 336 ± 3 494 ± 13 50.5 ± 3.0 147 ± 6 32.7 ± 5.8 0.13 ± 0.02 0.91 ± 0.02
Diabetic (12) 335 ± 2 439 ± 9 58.0 ± 3.8 478 ± 35a 192.3 ± 18.4a 0.37 ± 0.05a 1.95 ± 0.06a
Diabetic + salsalate (12) 333 ± 3 451 ± 12 48.0 ± 3.5 443 ± 40a 125.1 ± 25.9 0.36 ± 0.03a 1.73 ± 0.20a
Diabetic + menhaden oil 10% (12) 322 ± 3 420 ± 9 48.9 ± 3.3 469 ± 20a 246.4 ± 30.2a 0.42 ± 0.06a 1.53 ± 0.17a
Diabetic + menhaden oil 10% + salsalate (12) 326 ± 2 439 ± 21 50.9 ± 3.2 396 ± 43a 102.4 ± 25.0 0.32 ± 0.05a 1.55 ± 0.17a
Diabetic + menhaden oil 25% (12) 309 ± 4 426 ± 21 64.5 ± 4.6 500 ± 16a 316.9 ± 37.5a 0.41 ± 0.04a 2.81 ± 0.22a
Diabetic + menhaden oil 25% + salsalate (12) 305 ± 4 415 ± 14 58.2 ± 3.8 478 ± 39a 119.4 ± 26.2 0.35 ± 0.03a 1.78 ± 0.15a
Diabetic + menhaden oil 45% (12) 335 ± 3 459 ± 18 57.9 ± 4.3 426 ± 42a 82.6 ± 13.0a,b 0.40 ± 0.06a 1.96 ± 0.14a
Diabetic + menhaden oil 45% + salsalate (12) 315 ± 5 438 ± 14 67.2 ± 5.7 431 ± 35a 68.9 ± 18.6b 0.17 ± 0.04 1.33 ± 0.18

Data are presented as the mean ± SEM. aP < 0.05 compared to control rats. bP < 0.05 compared to diabetic rats. Parentheses indicate the number of experimental animals.