Table 4.
Association between rs2494732 and rs3803304 polymorphisms and breast cancer risk among cases and controls.
| Mutations | Genotypes | Cases (n = 91), n (%) |
Controls (n = 185), n (%) |
OR | 95% CI | P value | FDR Q value |
|---|---|---|---|---|---|---|---|
| rs2494732 | CC a | 41 (45) | 56 (30) | 1.0 | Reference | ||
| CT | 37 (41) | 89 (48) | 0.6 | 0.3 – 1.0 | P > 0.05 | Q > 0.05 | |
| TT | 13 (14) | 40 (22) | 0.4 | 0.2 – 0.9 | P ≤ 0.05 | Q > 0.05 | |
| CT+TT | 50 (55) | 129 (70) | 0.5 | 0.3 – 0.9 | P ≤ 0.05 | Q > 0.05 | |
|
| |||||||
| rs3803304 | CC a | 54 (59) | 121 (65) | 1.0 | Reference | ||
| CG | 30 (33) | 61 (33) | 1.1 | 0.6 – 1.9 | P > 0.05 | Q > 0.05 | |
| GG | 7 (8) | 3 (2) | 5.2 | 1.3 – 20.9 | P ≤ 0.05 | Q > 0.05 | |
| CG+GG | 37 (41) | 64 (35) | 1.3 | 0.8 – 2.2 | P > 0.05 | Q > 0.05 | |
OR, odds ratio; CI, confidence interval; FDR, false discovery rate.
aReferences.