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. Author manuscript; available in PMC: 2019 Jun 22.
Published in final edited form as: Curr Diab Rep. 2018 Jun 22;18(8):57. doi: 10.1007/s11892-018-1025-1

Table 1:

Genetic variants associated with glycemic traits and/or type 2 diabetes in youth

Marker Nearest gene Trait Reference(s)
rs560887 G6PC2 FG, HB 17–19
rs10830963 MTNR1B FG, HB 17–19
rs4607517 GCK FG, HB 17–19
rs13266634 SLC30A8 FG 18,19
rs7034200 GLIS3 FG 19
rs340874 PROX1 FG 19
rs11920090 SLC2A2 FG 19
rs11708067 ADCY5 FG 19
rs11605924 CRY2 FG 19
rs7903146 TCF7L2 IS, IGT/T2D*; T2D 20,21
rs4402960 IGF2BP2 IS, IGT/T2D* 20
rs7754840 CDKAL1 IS, IGT/T2D* 20
rs1111875 HHEX IS, IGT/T2D* 20
rs1169288 HNF1A IS, IGT/T2D* 20

Legend: FG, fasting glucose; HB = HOMA-B; IS, insulin secretion; IGT, impaired glucose tolerance; T2D, type 2 diabetes;

*

association assessed as part of genetic risk score