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. 2018 Jul 18;13(7):e0200270. doi: 10.1371/journal.pone.0200270

Table 3. ROC analysis of diagnostic indicators in differentiating nodules of papillary thyroid carcinoma from benign thyroid nodules.

Subgroups Diagnostic indicators Cutoff value AUC 95% CI Sensitivity (%) 95% CI Specificity (%) 95% CI
PTCs
(n = 52)		 SIRb0 ≤ 1.32 0.730 0.639–0.809 65.38 50.9–78.0 74.19 61.5–84.5
SIRb800 > 1.29 0.660 0.565–0.746 76.92 63.2–87.5 56.45 43.3–69.0
SIRb2000 > 1.17 0.842 0.761–0.903 94.23 84.1–98.8 64.52 51.3–76.3
ADCb0-800, mm2/sec ≤ 1.69 0.896 0.825–0.946 92.31 81.5–97.9 80.65 68.6–89.6
ADCb0-2000, mm2/sec ≤ 1.18 0.940 0.880–0.976 96.15 86.8–99.5 85.48 74.2–93.1
ADCb0-800-2000, mm2/sec ≤ 1.16 0.944 0.884–0.978 96.15 86.8–99.5 85.48 74.2–93.1
PTMCs
(n = 33)		 SIRb0 ≤ 1.32 0.797 0.702 - 0.873 78.79 61.1–91.0 74.19 61.5–84.5
SIRb2000 >1.17 0.814 0.721 - 0.886 90.91 75.7–98.1 64.52 51.3–76.3
ADCb0-800, mm2/sec ≤ 1.67 0.892 0.811 - 0.946 93.94 79.8–99.3 80.65 68.6–89.6
ADCb0-2000, mm2/sec ≤ 1.18 0.935 0.865 - 0.975 93.94 79.8–99.3 85.48 74.2–93.1
ADCb0-800-2000, mm2/sec ≤ 1.16 0.940 0.871 - 0.978 93.94 79.8–99.3 85.48 74.2–93.1

Abbreviations: PTCs, papillary thyroid carcinomas; PTMCs, papillary thyroid microcarcinomas; SIR, signal intensity ratio; ADC, apparent diffusion coefficient; AUC, area under curve; CI, confidence interval.