Table 3. Immunological parameters in patients of ACLF, CLF and HC.
| Parameter | ACLF(n = 38) | CLF(n = 38) | HC (n = 10) | ACLF vs. CLF | ACLF vs. HC | CLF vs. HC |
|---|---|---|---|---|---|---|
| p value | ||||||
| HLA-DR expression (MFI) | 30.34±29.32 | 41.71±52.13 | 50.60±13.96 | 0.42 | 0.04 | 0.59 |
| Mean percentage of monocytes expressing HLA-DR | 43.61±26.56% | 43.10±20.98% | 77.80±3.55% | 0.91 | <0.0001 | <0.0001 |
| Quantitative increase in the NOB | 16.55±11.91 | 17.24±16.18 | 50.39±45.98 | 0.47 | <0.0001 | 0.001 |
| IL-1 (pg/ml) ±SD | 3.50±2.67 | 0.35±1.12 | - | <0.0001 | - | - |
| IL-10 (pg/ml) ±SD | 3.28±3.68 | 0.45±0.62 | - | <0.0001 | - | - |
| TNF-α (pg/ml) ±SD | 3.27±2.94 | 0.35±1.12 | - | <0.0001 | - | - |
| IL-6 (pg/ml) ±SD | 220.9±611.2 | 16.51±16.52 | - | <0.0001 | - | - |
| IL-8 (pg/ml) ±SD | 781.7±865.1 | 48.85±62.06 | - | <0.0001 | - | - |
| IL-12 (pg/ml) ±SD | 0.98±1.14 | 0.10±0.27 | - | <0.0001 | - | - |
HLA-DR: Human Leukocyte Antigen—antigen D Related, MFI: Mean fluorescent intensity, NOB: Neutrophilic oxidative burst, IL: Interleukin