Table 2. Ten-year CAC progression by baseline AMD status (No AMD vs. Any AMD).
| Baseline CAC = 0 | Incident CAC, n (%) | Age, gender, time between CT scans adjusted OR (95% CI) | Multivariable* adjusted OR (95% CI) |
|---|---|---|---|
| No AMD(n = 1693) | 761 (45%) | ref | ref |
| Any AMD(n = 46) | 21 (46%) | 0.71 (0.38, 1.31) | 0.78 (0.42,1.47) |
| Baseline CAC>0 | Progression of CAC (CAC5-CAC1) (mean ± SD) | Robust regression model, Age, gender, time between CT scans adjusted (diff (se), p) | Multivariable robust regression model,(diff (se), p) |
| No AMD(n = 1170) | 339 ± 426 | ref | ref |
| Any AMD(n = 46) | 530 ± 537 | 101 (40), 0.011 | 114 (39), 0.004 |
Abbreviations: AMD = age-related macular degeneration; CAC = coronary artery calcium.
*adjusting for time between scans, age, gender, race, SBP, hypertension med, smoking status (never, former vs. current), total cholesterol, HDL cholesterol, lipid lowering med, CRP, diabetic status and education (high school or higher).