Table 3. Ten-year CAC progression by baseline AMD status (No AMD vs. Early/Late AMD).
| Baseline CAC = 0 | Incident CAC, n (%) | Age, gender, time between CT scans adjusted OR (95% CI) | Multivariable* adjusted OR (95% CI) |
|---|---|---|---|
| No AMD (n = 1693) | 761 (45%) | ref | ref |
| AMD early (n = 44) | 20 (45%) | 0.70 (0.38, 1.31) | 0.78 (0.41, 1.48) |
| AMD late (n = 2) | 1 (50%) | 0.69 (0.04, 11.60) | 0.84 (0.05, 15.01) |
| Baseline CAC>0 |
Progression of CAC (CAC5-CAC1) (mean ± SD) |
Robust regression model, Age, gender, time between CT scans adjusted(diff (SE), p-value) | Multivariable robust regression model,(diff (SE), p-value) |
| No AMD (n = 1170) | 339 ± 426 | ref | ref |
| AMD early (n = 39) | 529 ± 532 | 102 (43), 0.018 | 116 (42), 0.006 |
| AMD late (n = 7) | 539 ± 607 | 99 (99), 0.319 | 104 (97), 0.283 |
Abbreviations: AMD = age-related macular degeneration; CAC = coronary artery calcium.
*adjusting for time between scans, age, gender, race, SBP, hypertension med, smoking status (never, former vs. current), total cholesterol, HDL cholesterol, lipid lowering med, CRP, diabetic status.