ABL1 |
ABL Proto-Oncogene 1 |
3.88×10−3
|
Involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. |
ATR |
ATR Serine/Threonine Kinase |
8.88×10−16
|
Phosphorylates checkpoint kinases (CHK1, RAD17 and RAD9) as well as tumor suppressor protein (BRCA1). |
CCR6 |
C-C Motif Chemokine Receptor 6 |
1.56×10−4
|
Important for B-lineage maturation and antigen-driven B-cell differentiation, and regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. |
CD86 |
T-lymphocyte activation antigen CD86 |
6.24×10−3
|
Expressed by antigen-presenting cells; the ligand for CD28 antigen and cytotoxic T-lymphocyte-associated protein. |
EDNRA |
Endothelin Receptor Type A |
1.02×10−2
|
G protein-coupled receptor activating a phosphatidylinositol-calcium second messenger system. |
EDNRB |
Endothelin Receptor Type B |
7.38×10−5
|
G protein-coupled receptor activating a phosphatidylinositol-calcium second messenger system. |
EGFR |
Epidermal Growth Factor Receptor |
1.31×10−4
|
Essential for ductal development of the mammary glands. |
EPHA4 |
Ephrin Receptor A4 |
1.76×10−2
|
Implicated in mediating developmental events, particularly in the nervous system. |
EPHA5 |
Ephrin Receptor A5 |
3.88×10−2
|
Implicated in mediating developmental events, particularly in the nervous system. |
EPHB2 |
Ephrin Receptor B2 |
1.16×10−2
|
Previously associated with Prostate Cancer/Brain Cancer Susceptibility, Somatic and Prostate Cancer. |
FPR1 |
Formyl Peptide Receptor 1 |
2.78×10−2
|
Mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation. |
GRIK5 |
Glutamate Ionotropic Receptor Kainate Type Subunit 5 |
2.45×10−2
|
Previously associated with Schizophrenia. |
ITPR1 |
Inositol 1,4,5-Trisphosphate Receptor Type 1 |
5.95×10−3
|
Mediates calcium release from the endoplasmic reticulum. |
NCOA3 |
Nuclear Receptor Coactivator 3 |
2.84×10−3
|
Previously associated with Breast Cancer and Meningothelial Meningioma. |
NR2C1 |
Nuclear receptor subfamily 2 group C member 1 |
5.21×10−3
|
Function in many biological processes such as development, cellular differentiation and homeostasis. |
NR2C2 |
Nuclear Receptor Subfamily 2 Group C Member 2 |
1.21×10−2
|
Function in many biological processes such as development, cellular differentiation and homeostasis. |
P2RX4 |
Purinergic Receptor P2X 4 |
6.05 x10-12
|
A ligand-gated ion channel with high calcium permeability. |
RYK |
Receptor-Like Tyrosine Kinase |
1.41×10−2
|
Previously associated with Robinow Syndrome, Autosomal Dominant 1 and Multiple Endocrine Neoplasia, Type Iib. |