Table 4. Reporter transcription factors associated with the core genes of cervical cancer (p < 0.05).

Reporter transcription factor	Name	p-value	# of targeted genes	Association of the transcription factor with human diseases
E2F4	E2F Transcription Factor 4	0.013	91	Over-expression was associated with breast and colon cancers; mutation was associated with endometrial, prostate, colorectal, and gastric cancers as well as ulcerative colitis-associated neoplasm; amplification was associated with bladder cancer [47–49].
ETS1	ETS Proto-Oncogene 1	0.014	184	Up-regulation has been linked with cervical, breast and ovarian cancers [50].
CUTL1	Cut Like Homeobox 1	0.022	3	Over-expression was reported in high-grade carcinomas, and cause tubule formation obstruction in breast cancer [51].