Table 1. Number of miRNA targets to the differentially expressed miRNAs following infection with virulent, attenuated or saprophyte Leptospira.
(CT = control; FC = fold change).
| miRNAs | Virulent x CT | Attenuated X CT | Saprophyte X CT | Number of Targets | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FC | p-value | FC | p-value | FC | p-value | ||||||||||
| miR-155-3p | 14.3 | 0.000066 | 14.4 | 0.000006 | 6.3 | 0.000286 | 2 | ||||||||
| miR-155-5p | 12.1 | 0.000004 | 12.4 | 2.46E-07 | 5.9 | 0.000007 | 224 | ||||||||
| miR-221-5p | 1.8 | 0.012387 | 1.7 | 0.005452 | 1.6 | 0.009546 | 298 | ||||||||
| miR-1946b | 1.5 | 0.002698 | 2.0 | 0.000014 | 1.4 | 0.000770 | - | ||||||||
| miR-3473b | 1.6 | 0.003419 | 1.5 | 0.006212 | 1.2 | 0.038841 | - | ||||||||
| miR-1946a | 1.5 | 0.00278 | 1.8 | 0.001035 | 1.1 | 0.490372 | - | ||||||||
| miR-203-3p | 2.3 | 0.000001 | 1.5 | 0.019451 | -1.1 | 0.312029 | 5 | ||||||||
| miR-222-3p | 1.5 | 0.000009 | 1.5 | 0.00003 | 1.3 | 0.000024 | 177 | ||||||||
| miR-7667-3p | 3.2 | 0.021577 | 4.7 | 0.005985 | 2.4* | 0.031972 | 219 | ||||||||
| miR-7069-3p | 1.6 | 0.010383 | 1 | 0.350463 | 1 | 0.488653 | 189 | ||||||||
| mir-3473c | 1.5 | 0.009386 | 1.65 | 0.051234 | 1 | 0.868143 | - | ||||||||
| mir-7676-1 | 1.5 | 0.001562 | 1.3 | 0.018375 | 1.1 | 0.092322 | - | ||||||||
| mir-7676-2 | 1.5 | 0.001562 | 1.3 | 0.018375 | 1.1 | 0.092322 | - | ||||||||
| miR-1894-5p | 1.5 | 0.00436 | 1 | 0.096391 | 1.2 | 0.082984 | - | ||||||||
| miR-702-5p | -1.5 | 0.001429 | -1 | 0.416406 | -1.1 | 0.162260 | 64 | ||||||||
| miR-7053-3p | -1.5 | 0.006674 | -1.7 | 0.411229 | -1.1 | 0.162706 | - | ||||||||
| miR-6987-3p | 1.3 | 0.204396 | 1.8 | 0.006432 | 1.3 | 0.242025 | 78 | ||||||||
| miR-6370 | 2 | 0.076150 | 1.6 | 0.0016 | 1.71 | 0.068848 | - | ||||||||
| mir-717 | 1 | 0.441789 | 1.5 | 0.010607 | -1 | 0.799834 | - | ||||||||
| miR-7067-5p | -1.3 | 0.127036 | -1.8 | 0.010926 | -1.9 | 0.218096 | 730 | ||||||||
| mir-124-3 | -1.4 | 0.107360 | -1.9 | 0.010232 | 1 | 0.697852 | - | ||||||||
| mir-124-1 | 1 | 0.580372 | -1.9 | 0.010232 | 1 | 0.697852 | - | ||||||||
| mir-124-2 | -1.4 | 0.107370 | -1.9 | 0.010232 | -1 | 0.909340 | - | ||||||||
| miR-222-5p | 1.5* | 0.041164 | 1.5 | 0.111593 | 1.6 | 0.004998 | - | ||||||||
| miR-7119-3p | 1 | 0.589778 | - 1 | 0.867308 | -1.5 | 0.005767 | - | ||||||||
| miR-5100 | -1 | 0.183061 | 1.2 | 0.067205 | -1.5 | 0.000297 | - | ||||||||
| miR-2137 | - 1 | 0.453161 | -1.3 | 0.073805 | -1.6 | 0.0031 | - | ||||||||
|
mir-5046 |
- 1 | 0.666151 | -1.6 | 0.122672 | 1.6 | 0.007021 | - | ||||||||
| miR-8100 | 1.7 | 0.005375 | 1.25 | 0.110823 | 1.58 | 0.007021 | - | ||||||||