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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Trends Neurosci. 2018 Jun;41(6):327–330. doi: 10.1016/j.tins.2018.03.012

Figure 2.

Figure 2

Model for the action of Ca2+•syt 1 during exocytosis. At rest, vesicles are docked; upon stimulation, Ca2+ (orange spheres) enters and binds to syt1 (C2A rendered in green; C2B rendered in blue; the transmembrane domain is yellow). Ca2+·syt1 rapidly penetrates the target membrane to accelerate SNARE (shown in purple, red, and peach) catalyzed membrane fusion [12, 15].