The Atherosclerosis Risk in Communities study (ARIC) is a prospective study of cardiovascular disease (CVD) in 15,792 middle-aged adults recruited from four US communities in 1987–1989. The current study was conducted among participants in ARIC visit 4 (1996–1998). Of 11,656 eligible individuals, we excluded those with self-reported race neither white nor black (n=31) and African American participants at the Minnesota and Washington County field centers (n=38) because of small enrollment numbers, individuals missing data for low-density lipoprotein triglyceride (LDL-TG), remnant-like particle cholesterol (RLP-C), or other covariates (n=1524), and those with prevalent coronary heart disease (CHD) (n=632) or ischemic stroke (n=97) at visit 4. Therefore, 9334 individuals were included in this analysis.