Table 3B. Association of CHD, ischemic stroke, and CVD events competing with nonevent death across quartiles of LDL-TG.
Model | LDL-TG (mg/dL) | P trend of linearity | ||||
---|---|---|---|---|---|---|
Q1 (0.7–17) | Q2 (17.1–22.6) | Q3 (22.7–29.6) | Q4 (29.7–104) | |||
CHD | n/N (%) | 257/2360 (10.89) | 326/2342 (13.92) | 403/2301 (17.51) | 448/2331 (19.22) | <0.001 |
Model 1 | Reference | 1.30 (1.10-1.53) | 1.69 (1.45-1.98) | 2.02 (1.73-2.36) | <0.0001 | |
Model 2 | Reference | 1.08 (0.91-1.28) | 1.22 (1.03-1.45) | 1.23 (1.02-1.47) | 0.07 | |
Ischemic stroke | n/N (%) | 98/2360 (4.15) | 123/2342 (5.25) | 101/2301 (4.39) | 161/2331 (6.91) | <0.001 |
Model 1 | Reference | 1.34 (1.03-1.75) | 1.13 (0.85-1.49) | 1.85 (1.43-2.38) | <0.0001 | |
Model 2 | Reference | 1.28 (0.97-1.69) | 1.02 (0.75-1.38) | 1.58 (1.17-2.15) | 0.002 | |
CVD | n/N (%) | 327/2360 (13.86) | 420/2342 (17.93) | 472/2301 (20.51) | 566/2331 (24.28) | <0.001 |
Model 1 | Reference | 1.35 (1.17-1.56) | 1.59 (1.38-1.83) | 2.04 (1.78-2.34) | <0.0001 | |
Model 2 | Reference | 1.16 (1.00-1.35) | 1.20 (1.03-1.40) | 1.33 (1.13-1.57) | 0.007 |
Data presented as hazard ratio (95% confidence interval) using the first (lowest) quartile as the referent. Model 1 was adjusted by age, gender, and race; model 2 (Pooled Cohort Equation model) was model 1 plus total cholesterol, HDL-C, systolic blood pressure, anti-hypertensive medication use, current smoking, and diabetic status.