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. Author manuscript; available in PMC: 2019 Jul 10.
Published in final edited form as: J Am Coll Cardiol. 2018 Jul 10;72(2):156–169. doi: 10.1016/j.jacc.2018.04.050

Table 3B. Association of CHD, ischemic stroke, and CVD events competing with nonevent death across quartiles of LDL-TG.

Model LDL-TG (mg/dL) P trend of linearity
Q1 (0.7–17) Q2 (17.1–22.6) Q3 (22.7–29.6) Q4 (29.7–104)
CHD n/N (%) 257/2360 (10.89) 326/2342 (13.92) 403/2301 (17.51) 448/2331 (19.22) <0.001
Model 1 Reference 1.30 (1.10-1.53) 1.69 (1.45-1.98) 2.02 (1.73-2.36) <0.0001
Model 2 Reference 1.08 (0.91-1.28) 1.22 (1.03-1.45) 1.23 (1.02-1.47) 0.07
Ischemic stroke n/N (%) 98/2360 (4.15) 123/2342 (5.25) 101/2301 (4.39) 161/2331 (6.91) <0.001
Model 1 Reference 1.34 (1.03-1.75) 1.13 (0.85-1.49) 1.85 (1.43-2.38) <0.0001
Model 2 Reference 1.28 (0.97-1.69) 1.02 (0.75-1.38) 1.58 (1.17-2.15) 0.002
CVD n/N (%) 327/2360 (13.86) 420/2342 (17.93) 472/2301 (20.51) 566/2331 (24.28) <0.001
Model 1 Reference 1.35 (1.17-1.56) 1.59 (1.38-1.83) 2.04 (1.78-2.34) <0.0001
Model 2 Reference 1.16 (1.00-1.35) 1.20 (1.03-1.40) 1.33 (1.13-1.57) 0.007

Data presented as hazard ratio (95% confidence interval) using the first (lowest) quartile as the referent. Model 1 was adjusted by age, gender, and race; model 2 (Pooled Cohort Equation model) was model 1 plus total cholesterol, HDL-C, systolic blood pressure, anti-hypertensive medication use, current smoking, and diabetic status.