Table 3C. Association of CHD, ischemic stroke, and CVD events with RLP-C and LDL-TG as continuous variables.
Incident Event | Model | RLP-C | LDL-TG | ||
---|---|---|---|---|---|
Hazard ratio (95% confidence interval) | P | Hazard ratio (95% confidence interval) | P | ||
CHD | Model 1 | 1.26 (1.19–1.34) | <0.001 | 1.97 (1.73–2.24) | <0.001 |
Model 2 | 0.99 (0.92–1.06) | 0.73 | 1.28 (1.10–1.50) | 0.002 | |
Model 3 | 0.85 (0.76–0.96) | 0.008 | 1.27 (1.07–1.50) | 0.006 | |
Ischemic stroke | Model 1 | 1.18 (1.07–1.30) | 0.001 | 1.64 (1.32–2.04) | <0.001 |
Model 2 | 1.05 (0.93–1.18) | 0.46 | 1.47 (1.13–1.92) | 0.005 | |
Model 3 | 0.82 (0.68–1.01) | 0.058 | 1.36 (1.01–1.82) | 0.040 | |
CVD | Model 1 | 1.25 (1.19–1.32) | <0.001 | 1.94 (1.73–2.17) | <0.001 |
Model 2 | 1.00 (0.94–1.06) | 0.97 | 1.35 (1.17–1.55) | <0.001 | |
Model 3 | 0.84 (0.76–0.93) | 0.001 | 1.31 (1.13–1.53) | <0.001 |
Data are presented as hazard ratio (per Ln unit increase for RLP-C and LDL-TG) and 95% confidence interval. Exposure values assessed as continuous variables. Model 1 was adjusted by age, gender, and race; model 2 (Pooled Cohort Equation model) was model 1 plus total cholesterol, HDL-C, systolic blood pressure, antihypertensive medication use, current smoking, and diabetes mellitus; model 3 was model 2 plus log-triglycerides.